Officers responded to the 2600 block of Greenmount Avenue for a report of a shooting at 9:45 p.m. Friday.
The victim identified as 32-year-old Keith Ramsey was found suffering from a gunshot wound.
Ramsey was transported to a local hospital where he died.
Eastern district police officers responded to the 1100 block of Curtain Street for a report of an unresponsive person at 11:58 p.m. Friday.
Officers found a man suffering from a gunshot wound to the head, he was pronounced dead on the scene.
A Northeast district patrol officer was conducting a vehicle stop in the 2700 block of Harford Road at 1:21 a.m. Saturday, when he heard several gunshots in the area.
Officers searched the area, coming to the 2600 block of Harford Road at Homestead Street where they found the victim, a 26 year-old male unresponsive.
An investigation revealed that the victim was shot by an unidentified suspect, police said.
The victim then walked out into the street where he was stuck by a vehicle that fled the scene.
Medics transported the victim to an area hospital where he was pronounced dead.
Homicide detectives are asking anyone with information to contact them at 410-396-2100 or Metro Crime Stoppers at 1-866-7lockup.